CRISPR guide RNA design for research applications
نویسندگان
چکیده
منابع مشابه
CRISPR guide RNA design for research applications
The rapid rise of CRISPR as a technology for genome engineering and related research applications has created a need for algorithms and associated online tools that facilitate design of on-target and effective guide RNAs (gRNAs). Here, we review the state of the art in CRISPR gRNA design for research applications of the CRISPR-Cas9 system, including knockout, activation, and inhibition. Notably...
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ژورنال
عنوان ژورنال: The FEBS Journal
سال: 2016
ISSN: 1742-464X,1742-4658
DOI: 10.1111/febs.13777